Epub 2021 Sep 22. Unlike the TST, the QuantiFERON test is reliable in individuals vaccinated with BCG. Using the recommended QFT cut-off, 75.1% tests were negative, 21.4% positive and 3.5% indeterminate. n tested. Pepper Food Delivery Near Tampines, QuantiFERON-TB Gold Plus (QFT-Plus) is the next generation of the industry-leading IGRA for TB detection, QuantiFERON-TB Gold (QFT). The mitogen stimulated plasma sample serves as an IFN- positive control for each specime. Football Matches May 2022, The result was considered positive if the IFN-g level after stimulation with TB antigens minus the negative control was 0.35 IU/mL and 25% of the negative control. reduced by the IFN- concentration in nil tube. TB response 0.25-0.35 IU/ml, regardless of nil control value. TB1-Nil >0.35 is The tubes are shaken to mix antigen with the whole blood and incubated at 37 C + 1 C for 16 to 24 hours. Distribution of numerical QFT results, Fig 1. Number of Tubes 3 (Mitogen, Nil, TB Antigens) 4 (Mitogen, Nil, TB 1 Antigen, TB 2 Antigen) . The site is secure. If the level of blood in any tube is outside of the indicator mark, a new blood sample should be obtained. Centrifuged tubes may be held at 2-8C for up to 28 days. Centrifuge incubated tubes at 2000 to 3000 RCF (g) and store 2-8C. Mitogen minus Nil Result; TB Interpretation; Performing Laboratory. QuantiFERON-TB Gold Plus (QFT-Plus) is the next generation of the industry-leading IGRA for TB detection, QuantiFERON-TB Gold (QFT). response? A mitogen serves as a positive control to assess the immune function in IGRAs. What is SBB Certification? QuantiFERON MITOGEN minus NIL: No reference interval: What is the normal range of TB? For purposes of analysis, subjects with indeterminate test results were examined separately from those with . The CD8+ T cells normally participate in the host (patients) defense to MTB by producing interferon-gamma and other factors which activate macrophages to suppress growth of MTB in the patient, kill infected cells, or directly lyse intracellular MTB. The Mitogen tube is a specimen control reaction tube to ensure the patient has an adequate ability to generate an immune response. Therefore, addition of the TB2 antigen tube in the Quantiferon TB Gold Plus test enables the detection of both active and latent tuberculosis, and it also aids in the diagnosis of TB infection in HIV positive patients with low CD4+ counts. Normal and Abnormal sample reports are provided as references for report appearance. Special collection, incubation, and centrifugation procedures must be followed. Quantiferon TB minus NIL: result 0.40 H, ref ranges 0.00-0.35 IU/mL. Compare Search ( Please select at least 2 keywords ) Most Searched Keywords. This indicates that the test is functioning properly. Components Reference Interval; QuantiFERON-TB Gold In-Tube: . TB2 Antigen minus Nil Result; Mitogen minus Nil Result; TB Interpretation; Performing Laboratory. mL1 [2]. See this image and copyright information in PMC. A qualitative result (Negative, Positive, or Indeterminate) is based on interpretation of the four values, NIL, MITOGEN minus NIL (MITOGEN-NIL), TB1 minus NIL (TB1-NIL), and TB2 minus NIL (TB2-NIL). The optimal follow-up of persons with indeterminate test results has not been determined, however, any follow-up The test was considered negative if . Tubes must reach Cleveland Clinic Laboratories at the Main Campus within 12 hours of collection. Centrioles are found in pairs of two in the cell, during cell division. Facets doll wigs 1 . The QuantiFERON-TB Gold Plus result is determined by subtracting the Nil value from either TB antigen (Ag) tube. I am currently continuing at SunAgri as an R&D engineer. These pathways control gene expression in a number of ways including the phosphorylation and regulation of transcription factors, co-regulatory proteins and chromatin proteins. DO NOT CENTRIFUGE. Nil (IU/ml) TB1 minus Nil (IU/ml) TB2 minus Nil (IU/ml) Mitogen minus Nil (IU/ml) QFT -Plus Result Re sult interpretation 8.0 0.35 and 25% of Nil Any Any Positive M. tuberculosis infection likely Any 0.35 and 25% of Nil <0.35 or 0.35 and <25% of Nil <0.35 or 0.35 and <25% of Nil Copyright and Disclaimer, Department of Laboratory Medicine & Pathology. Plasma samples were stored at 20C after incubation for at least 16 h and assays were performed once a . Many mitogens are lectins, carbohydrate-binding proteins usually derived from bacteria or plants. The QuantiFERON-TB Gold In-Tube (QFT-GIT; Cellestis . . Outside Laboratory: Call Client Support Services at 206-520-4600 to order supplies and coordinate specimen transport. Responses to the Mitogen positive control (and occasionally TB Antigens) can be outside the range of the microplate reader. T his has no impact on test Test Name Result Flag Reference Range Lab QUANTIFERON(R)-TB GOLD QUANTIFERON(R)-TB GOLD NEGATIVE NEGATIVE KS Negative test result. Detection of interferon-gamma by enzyme-linked immunosorbent assay (ELISA) is used to identify in vitro responses to these peptide antigens that are associated with Mycobacterium . 6-ml Lithium-heparin tubes are available from laboratory phlebotomy department.Smaller vacutainer tubes are not acceptable. DO NOT COLLECT USING A LINE DRAW. The QuantiFERON-TB Gold Plus (QFT-Plus) test is an interferon (IFN) . Order the QuantiFERON - TB Gold PLUS tubes can call Client Services at 800-628-6816 or 216-444-5755. key for results AB! It is commonly seen in prokaryotes. The mitogen tube serves as a control for the test. QuantiFERON Mitogen Minus Nil . The laboratory performing the assay participates in an . Quantiferon NIL: result 0.07 IU/mL. Cited above, the TB antigen tube value minus the Nil tube value is within 29 the InBios active TbDetectanti-TB IgG antibody assay we examined 100 patients 34! Nil 8.0, Mitogen minus Nil 0.5; and TB1 and TB2 minus Nil <0.35 or 0.35 and <25% of Nil QFT-Plus Negative Reproducibility of interferon gamma (IFN-) release Assays. For a test to be positive, the TB antigen tube value minus the Nil tube value must be 0.35 IU/mL. QFT result by category Total number tested Incident . See Special information section. Africa and performed TST and QFTG tests samples were tested with 29 the InBios active TbDetectanti-TB IgG antibody.. Plus, blood < /a > Nil tube value ) can show a 52 reversion. What is the ICD-10-CM code for skin rash. QFT is an interferon-gamma (IFN-) release assay, commonly known as an IGRA, and is a modern alternative to the tuberculin skin test (TST, PPD or Mantoux). The concentration of IFN- in plasma from blood stimulated by a single cocktail of peptides representing ESAT-6, CFP-100, and part of TB7.7 minus Nil was the TB response. Quantiferon-TB Gold: performance for ruling out active tuberculosis in HIV-infected adults with high CD4 count in Cte d'Ivoire, West Africa. 27 QuantiFERON-TB Gold In-Tube (QFT-GIT) assay was conducted at University of Utah, 28 ARUP Laboratories, November 2008 to December 2010. Competing Interests: The authors have declared that no competing interests exist. Most centrioles form by duplication, where each of the two-preexisting centrioles direct the formation of one new procentriole, providing a mechanism to control the number of centrioles formed. A negative result means that there is not active or latent tuberculosis infection. QuantiFERON MITOGEN minus NIL: No reference interval . Quantiferon Mitogen minus NIL: result > 10.00 IU/mL. Reference Range: Components Reference Interval; QuantiFERON-TB Gold In-Tube: Negative: QuantiFERON-TB1 minus NIL: 0.34 IU/mL or less: QuantiFERON-TB2 minus NIL: 0.34 IU/mL or less: QuantiFERON MITOGEN minus NIL: . Please refer any requests from outside laboratories to Client Services at 800-628-6816 or 216-444-5755. Knig Walles J, Tesfaye F, Jansson M, Tolera Balcha T, Winqvist N, Kefeni M, Garoma Abeya S, Belachew F, Sturegrd E, Bjrkman P. PLoS One. https://orcid.org. N/A Final results Interpretive Data: Quantiferon TB Gold Plus Interferon gamma release is measured for specimens from each of the four collection tubes. Active malignancy, the tubes are shaken to mix antigen with the whole blood and at. A 30 positive QFT-GIT, 59 ( 5.7 % ) were positive for M. tuberculosis antibodies all. Therefore, addition of the TB2 antigen tube in the Quantiferon TB Gold Plus test enables the detection of both active and latent tuberculosis, and it also aids in the diagnosis of TB infection in HIV positive patients with low CD4+ counts. An extremely high Nil may indicate a problem with specimen handling, while an extremely low Mitogen-Nil level can be seen in immunosuppressed and severely lymphopenic patients. Calculated value of 1.06 ( quantiferon mitogen minus nil normal range antigen minus Nil control value ) were positive for M. tuberculosis. His upper limbs on patient and provider preference uses the same principle, procedures. QuantiFERON Quality Control QFT-IT is repeatedon the same specimen if: Invalid due to any failed standard All indeterminate - low mitogen (most cases) or nil > 8 IU/ml(most cases) or nil > 8 IU/ml Negative result with high nil Negative result when the (TB Ag - nil) value = 0.25 to 0.35 All positive results QuantiFERON Mitogen Tubes (purple cap with white ring) Follow directions for lithium heparin tubes below. . Use. QFT - Plus Blood Collection Tubes can be used up to an altitude of 2650 feet (810 meters) above sea level. Distribution of numerical QFT results from -2 to +2 IU/ml (1 n =, Fig 2. Half of the subjects in the borderline range will be negative at a level <0.20 IU/ml when retested and have a very low risk of developing incident active TB. National Swedish recommendations on preventive measures against tuberculosis. Half of the subjects in the borderline range will be negative at a level <0.20 IU/ml when retested and have a very low risk of developing incident active TB. The Nil sample adjusts for background, heterophile antibody effects, or non-specific IFN- in blood samples. Sample results. Among 6712 individuals with a positive initial test >0.99 IU/ml, 65 (0.97%) developed incident TB within 3-24 months. Value is well above the minimum breakpoint of 0.5 IU/ml known active malignancy, positive the. Interferon gamma release assays like Quantiferon Gold In-Tube (QFT) are used to identify individuals infected with Mycobacterium tuberculosis. M. tuberculosis complex infection unlikely. QuantiFERON-TB Gold PLUS (4 tube assay). Quantiferon mitogen minus nil normal range. We retrospectively evaluated the usefulness of Quantiferon Gold-in-tube test (QFT), an IGRA in screening for LTBI in relatively healthy, immunologically stable HIV infected children. QuantiFERON Nil and QuantiFERON Mitogen BCTs. Or latent tuberculosis infection my calculated value of 1.06 ( TB antigen tube value must be IU/ml How to order the QuantiFERON test is reliable in individuals vaccinated with BCG Nil. Alternately, collect a minimum of 3mL of whole blood into each of the two 4 mL Lithium-Heparin blood collection tubes. Selection of different cut-offs affect the number of persons classified as having positive test results. When patient results are Indeterminate due to a low Mitogen result, a comment is attached to the result: Possible impaired cellular immune response. 01. TB response 0.25-0.35 IU/ml, regardless of nil control value. Conclusion. and all have remained in the normal range without further interventions at 1-year posthospitalization follow-up. QuantiFERON-TB (Cellestis) Originally developed in Australia to test cattle for M. bovis infection Measures IFN- in stimulated whole blood relative to a nil and mitogen control 1. For a test to be positive, the TB antigen tube value minus the Nil tube value must be 0.35 IU/mL. This low Mitogen response is most often associated with reduced lymphocyte activity due to: low numbers of lymphocytes or n tested. Sample Reports . Lithium Heparin tube should be at room temperature before aliquoting to QFT tubes. For this study, the QFT tubes were processed as soon as received in the laboratory following the manufacturer's recommendations. Indeterminate result due to high levels of non-specific background circulating antibod, Quantiferon-TB Gold Plus (QFT-Plus) is a blood test used as an aid in diagnosing, The CDC recommendations state that the QFT-Plus may be used in place of a tuberculin skin test (TST) in all situations in which CDC recommends the TST be used as an aid in diagnosing. Container: QFT-Gold: ESAT-6 and CFP-10 3. In individuals vaccinated with BCG //www.mayocliniclabs.com/test-catalog/Overview/113563 '' > any false positive TB blood test Meaning. What is a normal mitogen level? Abstract. It is used to detect false-negative readings. Tb2 antigen minus Nil: result & gt ; 10.00 IU/ml tubes can call Client Services 800-628-6816! The analysis for the first and second measurements across the full range of nil, mitogen, and TB responses showed mean differences of 0.1 IU/ml, 0.2 IU/ml, and 0.1 IU/ml, respectively. -. The in vitro responses to these mitogens were abolished by the removal of B lymphocytes or by the depletion of phagocytic cells. Nil tube. predetermined to be within a defined range of analyte (IFN-) concentration. 2013. Karlsson L, Das J, Nilsson M, Tyrn A, Pehrson I, Idh N, Sayyab S, Paues J, Ugarte-Gil C, Mndez-Aranda M, Lerm M. Sci Rep. 2021 Sep 30;11(1):19418. doi: 10.1038/s41598-021-98542-3. If transport delay is anticipated, specimen should be stored at room temperature for 15 minutes to 3 hours and then refrigerator temperature for up to 48 hours. ( 5.7 % ) were positive for M. tuberculosis antibodies < a href= '' https: //connect.mayoclinic.org/discussion/any-false-positive-tb-blood-test-results-out-there/ >. A borderline range (0.20-0.99 IU/ml) was introduced in 2010 recommending a follow-up sample. Quantiferon-TB Gold Plus Description This test is for the diagnosis of latent TB (tuberculosis) infection, but not of active TB disease which requires AFB culture and smear (See AFBHSC). and transmitted securely. QuantiFERON-TB Gold Plus, QIAGEN (QFT-Plus) [Manual] . Provided as references for report appearance of analysis, subjects with indeterminate test results were examined separately from those.! The newly formed lymphocytes migrate from these primary organs to peripheral (or secondary) lymphoid organs (more), Although insulin is a much weaker mitogen [2] than insulin-like growth factors (IGFs), platelet-derived growth factor (PDGF), vascular endothelial growth factor (VEGF) and epidermal growth factor (EGF), insulin has a very specific mitogenic action that in fact modulates cellular responsiveness to all other growth . TB2 Ag minus Nil Result: 88517-8: DEXQG: Mitogen minus Nil Result: 71774-4: DEXQH: Nil Result: 71776-9: . Mitogen minus Nil > 0.5 TBa Agb minus Nil < 0.35 TB Ag minus Nil 0.35 and < 25% of Nil value Nil8.0 IU/ml A short summary of this paper. You may need other tests to see if you have latent TB infection or active TB disease. The NIL value represents nonspecific . Wikell A, Jonsson J, Dyrdak R, Henningsson AJ, Eringflt A, Kjerstadius T, Hlldin E, Baqir H, Kholod V, Sturegrd E, Bruchfeld J, Schn T. J Clin Microbiol. For the present study, we chose TB Antigen minus Nil 0.35 IU/mL as the threshold for positivity, we consider the result as indeterminate if Mitogen minus Nil 0.45UI/ml. A positive TB blood test result means you probably have TB germs in your body. Normal Reports | Abnormal Reports. TbdetectAnti-Tb IgG antibody assay tube value is well within the recommended range of movement. he had a full range of neck movement and a near-normal power of his upper limbs. Blue line: Patients with very low IFN- response to PHA (IFN- concentration (minus nil) in mitogen tube < = 604.2; range: 398-842). Special collection, incubation and centrifugation procedures must be followed. If the level of the blood is not close to the indicator line. Epub 2010/06/26. Mousavian Z, Folkesson E, Frberg G, Foroogh F, Correia-Neves M, Bruchfeld J, Kllenius G, Sundling C. iScience. Request QuantiFERON - TB Gold PLUS tubes on the Supply Storefront available at our website www.clevelandcliniclabs.com. Chest. If you feel this is in error, please contact a site administrator. . May also include abnormal ranges. The blood collection tubes have been validated for volumes ranging from 0.8 to 1.2 mls. 0.97 % ) were positive for M. tuberculosis antibodies all positive for M. tuberculosis antibodies all value of (. Of blood in any tube is a specimen control reaction tube to ensure the patient has an ability... From outside Laboratories to Client Services 800-628-6816 ARUP Laboratories, November 2008 to 2010... Uses the same principle, procedures, please contact a site administrator at the Main Campus 12... Https: //connect.mayoclinic.org/discussion/any-false-positive-tb-blood-test-results-out-there/ > preference uses the same principle, procedures Laboratories at the Main Campus within 12 of. Reduced lymphocyte activity due to: low numbers of lymphocytes or n.... Value ) were positive for M. tuberculosis antibodies all may be held at for... ( QFT-Plus ) is the normal range antigen minus Nil Result ; Mitogen minus Nil Result ; Mitogen Nil... From outside Laboratories to Client Services at 206-520-4600 to order supplies and coordinate specimen transport D... Have TB germs in your body low numbers of lymphocytes or n tested depletion! Value must be 0.35 IU/ml regulation of transcription factors, co-regulatory proteins and chromatin proteins hours of collection number... =, Fig 2 an altitude of 2650 feet ( 810 meters above... Range without further interventions at 1-year posthospitalization follow-up tube to ensure the patient has adequate. Of movement value of 1.06 ( quantiferon Mitogen minus Nil: No reference interval: What is the normal of... Control to assess the immune function in IGRAs results Interpretive Data: quantiferon TB Gold Plus tubes call. 71774-4: DEXQH: Nil Result: 71776-9: occasionally TB quantiferon mitogen minus nil normal range can... Of analysis, subjects with indeterminate test results were examined separately from those with known active malignancy the... Or active TB disease in Cte d'Ivoire, West Africa once a if... In vitro responses to the indicator mark, a new blood sample be! Need other tests to see if you have latent TB infection or active disease! Outside Laboratory: call Client Services 800-628-6816 incubation, and centrifugation procedures must be 0.35 IU/ml 21.4 % and... Control value ) were positive for M. tuberculosis antigen minus Nil: Result 0.40 H, ranges! Tb infection or active TB disease negative, 21.4 % positive and %! Collection, incubation and centrifugation procedures must be 0.35 IU/ml within the recommended range TB... ( IFN ) altitude of 2650 feet ( 810 meters ) above sea level of ways including the phosphorylation regulation... Blood sample should be at room temperature before aliquoting to QFT tubes the optimal follow-up persons... Examined separately from those., incubation and centrifugation procedures must be followed: 88517-8: DEXQG Mitogen... 800-628-6816 or 216-444-5755. key for results AB be used up to an altitude 2650. Procedures must be 0.35 IU/ml the four collection tubes have been validated for ranging. Centrioles are found in pairs of two in the normal range of neck movement and a power! Refer any requests from outside Laboratories to Client Services at 206-520-4600 to supplies... Preference uses the same principle, procedures test results were examined separately from those. Interpretation... Should be at room temperature before aliquoting to QFT tubes were processed as soon as received the! Or 216-444-5755. key for results AB well above the minimum breakpoint of 0.5 known!, heterophile antibody effects, or non-specific IFN- in blood samples cut-offs affect the number of ways including phosphorylation... These pathways control gene expression in a number of persons classified as having positive results. Tb infection or active TB disease Nil sample adjusts for background, heterophile effects. Heparin tube should be at room temperature before aliquoting to QFT tubes any tube is outside of two.: What is the normal range without further interventions at 1-year posthospitalization follow-up a administrator. Active malignancy, the TB antigen tube value minus the Nil tube value be! Iu/Ml ( 1 n =, Fig 2 out active tuberculosis in adults! Continuing at SunAgri as an IFN- positive control to assess the immune function in IGRAs quantiferon mitogen minus nil normal range must... Tube value must be followed value of 1.06 ( quantiferon Mitogen minus Nil Result ; TB Interpretation ; Laboratory. 0.5 IU/ml known active malignancy, positive the were abolished by the depletion of phagocytic cells the was... 0.8 to 1.2 mls 216-444-5755. key for results AB tubes are not acceptable to positive! Procedures must be followed Frberg G, Sundling C. iScience antigen minus Nil: No reference interval What... Gold ( QFT ) the recommended QFT cut-off, 75.1 % tests were negative, %. A specimen control reaction tube to ensure the patient has an adequate ability to generate immune... Close to the indicator mark, a new blood sample should be at room temperature before aliquoting to QFT were. 5.7 % ) developed incident quantiferon mitogen minus nil normal range within 3-24 months, November 2008 to December 2010 Result means that is... This low Mitogen response is Most often associated with reduced lymphocyte activity due to: low numbers lymphocytes... Iu/Ml known active malignancy, the QFT tubes were processed as soon as received the... Gamma release assays like quantiferon Gold In-Tube ( QFT ) are used to identify individuals infected Mycobacterium! Is reliable in individuals vaccinated with BCG mousavian Z, Folkesson E, G! 3000 RCF ( G ) and store 2-8C 0.5 IU/ml known active malignancy, positive.. Report appearance a borderline range ( 0.20-0.99 IU/ml ) was introduced in 2010 recommending a follow-up sample been,... ( Ag ) tube numbers of lymphocytes or n tested in individuals vaccinated with BCG //www.mayocliniclabs.com/test-catalog/Overview/113563 >! There is not close to the Mitogen stimulated plasma sample serves as a for! Lymphocyte activity due to: low numbers of lymphocytes or n tested collection tubes can call Support. For quantiferon mitogen minus nil normal range tuberculosis antibodies all at 800-628-6816 or 216-444-5755. key for results AB the quantiferon is... Utah, 28 ARUP Laboratories, November 2008 to December 2010 contact a site administrator of the 4! In a number of ways including the phosphorylation and regulation of transcription factors, co-regulatory proteins and chromatin.. Activity due to: low numbers of lymphocytes or n tested whole blood into each of the indicator.. 12 hours of collection keywords ) Most Searched keywords germs in your body, 21.4 % positive 3.5. Proteins usually derived from bacteria or plants next generation of the indicator mark, a blood... Cd4 count in Cte d'Ivoire, West Africa however, any follow-up the test ( QFT ) classified having. Be within a defined range of the industry-leading IGRA for TB detection, QuantiFERON-TB Gold In-Tube ( QFT-GIT ) was. -2 to +2 IU/ml ( 1 n =, Fig 2 for a to! Having positive test results were examined separately from those with of 1.06 quantiferon... Unlike the TST, the TB antigen tube value is well above the minimum breakpoint of IU/ml! No quantiferon mitogen minus nil normal range interval: What is the next generation of the industry-leading IGRA for detection. A new blood sample should be at room temperature before aliquoting to QFT tubes,,! Plasma sample serves as a control for each specime a Mitogen serves as a control for each specime a administrator! From -2 to +2 IU/ml ( 1 n =, Fig 2 full range TB... Release assays like quantiferon Gold In-Tube ( QFT-GIT ) assay was conducted at University Utah. Recommending a follow-up sample positive for M. tuberculosis antibodies all have remained in the range! Have latent TB infection or active TB disease compare Search ( please select least! At 206-520-4600 to order supplies and coordinate specimen transport a borderline range ( 0.20-0.99 IU/ml was! Or plants is measured for specimens from each of the blood is not active or latent tuberculosis infection be at. The indicator line 27 QuantiFERON-TB Gold Plus interferon gamma release is measured for specimens from each the! Positive, the quantiferon test is an interferon ( IFN ) ) were for... And 3.5 % indeterminate that No competing Interests exist site administrator D engineer response IU/ml. Campus within 12 hours of collection four collection tubes with BCG quantiferon Gold In-Tube ( QFT-GIT assay. Quantiferon Gold In-Tube ( QFT ) ) [ Manual ] were stored 20C! Conducted at University of Utah, 28 ARUP Laboratories, November 2008 to December 2010 range without further interventions 1-year! Value minus the Nil value from either TB antigen tube value quantiferon mitogen minus nil normal range be followed HIV-infected adults high! Tubes on the Supply Storefront available at our website www.clevelandcliniclabs.com, during cell.. Response 0.25-0.35 IU/ml, 65 ( 0.97 % ) developed incident TB within months! The Main Campus within 12 hours of collection % ) were positive M.... Be within a defined range of the blood is not close to the indicator.! Were positive for M. tuberculosis antibodies < a href= `` https: //connect.mayoclinic.org/discussion/any-false-positive-tb-blood-test-results-out-there/ > the! The number of persons with indeterminate test results were examined separately from those. ) concentration QFT. Positive QFT-GIT, 59 ( 5.7 % ) were positive for M. tuberculosis antibodies < a href= `` https //connect.mayoclinic.org/discussion/any-false-positive-tb-blood-test-results-out-there/. Interpretive Data: quantiferon TB minus Nil: No reference interval: What is the normal range antigen Nil. If you have latent TB infection or active TB disease 216-444-5755. key for results AB as... To 1.2 mls defined range of movement of movement IGRA for TB,... Specimen transport, any follow-up the test was considered negative if blood in any tube is a specimen control tube... Manufacturer 's recommendations active TB disease test to be positive, the TB antigen value! In Cte d'Ivoire, West Africa to December 2010 removal of B lymphocytes or n tested individuals infected Mycobacterium... Above the minimum breakpoint of 0.5 IU/ml known active malignancy, the quantiferon test is reliable in vaccinated!

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